Hemoglobin A1c (HbA1c) Test Kit

This assay is intended for the quantitative determination of mmol/mol hemoglobin (IFCC) and % hemoglobin A1c (DCCT/NGSP) in whole blood.

【Parameter】

【Technology highlight】

Chemiluminescence Reasonance Energy Transfer (CRET) Principle

【Intended Use】

In vitro test for the quantitative determination of mmol/mol hemoglobin (IFCC) and % hemoglobin A1c (DCCT/NGSP) in whole blood or hemolysate. HbA1c determinations are useful monitoring of long-term blood glucose control in individuals with diabetes mellitus. Moreover, this test is to be used as an aid in diagnosis of diabetes and identifying patients who may be at risk for developing diabetes. 

HbA1c is formed in two steps by the non-enzymatic reaction of glucose with the N-terminal amino group of the β-chain of normal adult Hb (HbA). The first step is reversible and yields labile HbA1c. This is rearranged to form stable HbA1c in a second reaction step. 

In the erythrocytes, the relative amount of HbA converted to stable HbA1c increases with the average concentration of glucose in the blood. The conversion to stable HbA1c is limited by the erythrocyte's life span of approximately 100 to 120 days. As a result, HbA1c reflects the average blood glucose level during the preceding 2 to 3 months. HbA1c is thus suitable to monitor long-term blood glucose control in individuals with diabetes mellitus. Glucose levels closer to the time of the assay have a greater influence on the HbA1c level.

【Advantage】

Low transport costs, no cold chain required.

Single packaging to avoid wasting reagents.

Long shelf-life of reagents, breaking through industry challenges.

【Principle】

Sandwich principle.

The Hemoglobin A1c (HbA1c) test kit employs a wash-free and homogeneous strategy based on proximity hybridization-regulated CRET(Chemiluminescence resonance energy transfer).

【Main Components】

10/20/25 Lyophilization sphere reagents

【Storage Conditions and Expiration Date】

Hemoglobin A1c (HbA1c) test kit can be stably stored for 18 months at 2-8℃ and protected from light. Apply reagent immediately after opening.

【Applicable Instruments】

Hemoglobin A1c (HbA1c) test kit Test Kit used for Chemiluminescence Immunoassay Analyzer (HSCL-5000) produced by Nanjing Poclight Biotechnology Co. Ltd.

【Display】

【Application Scenario】