【Product Name】

【Package specifications】

25 Tests /Box

【Intended use】

This Thyroxine (T4) Test Kit is manly used for in vitro quantitative determination of total thyroxine (TT4) content in human serum.

Thyroxine (T4) is a hormone synthesized and secreted by the thyroid gland, which plays an important role in the regulation mechanism. Thyroxine (T4) is combined with thyroglobulin and stored in the remnant cavity of thyroid follicles, secreted and released under the regulation of thyroid stimulating hormone (TSH), and participates in the circulation [1] . More than 99% of thyroxine (T4) in the serum is in the form of binding to thyroxine-binding globulin (TBG), albumin and other proteins.The concentration of transport protein in the serum is easily affected by exogenous and endogenous effects. Ignoring changes in the concentration of bound protein (such as pregnancy, taking estrogen or suffering from nephrotic syndrome, etc.) will lead to errors in the detection of thyroid metabolism. Results [2], [3]. Diseases in any part of the thyroid-pituitary hypothalamic system can cause excessive (hyperthyroidism) or insufficient (hypothyroidism) secretion of T4 or T3, Therefore, the determination of total thyroxine (T4) can be used for the diagnosis of primary and secondary hypothyroidism and the monitoring of thyroid stimulating hormone (TSH) suppression therapy [4] .

At present, the commonly used detection methods in laboratories include enzyme-linked immunoassay, immunofluorescence, colloidal gold and chemiluminescence.

【Accessories required but not provided】

♢ Immunofluorescence quantitative analyzer

♢ Reagent strip incubator

【Storage and stability】