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NGAL (neutrophil gelatinase-associated lipocalin, lipocalin-2, sidero- calin) is a novel biomarker for diagnosing acute kidney injury (AKI). Under normal conditions NGAL levels are low in urine and plasma Still, they rise sharply from basal levels in response to kidney injury to reach diagnostic levels within a very short time - as much as 24 hours or more before any signiﬁcant rise in serum creatinine.

Product Detail

Product Specification

Specimen Types	Urine
Specimen Capacity	10μL
Reaction Time	10min
Sample Capacity	80μL
Detection Range	10-5000ng/mL

Clinical Significance

Acute kidney injury (AKI) is one of the major causes of morbidity and mortality encountered by hospitalized patients, especially intensive care centers. Early detection may improve the hospital stay, patients prognosis, and reduce expensive medical costs.
Cited from: Cai-Mei Zheng, Min-Tser Liao et al.,“ Biomarkers in Acute
Kidney Injury”, Open Journal of Nephrology, Vol.3 No.1(2013).

Aplication

Early diagnosis of AKI to allow earlier initiation of appropriate management
Risk stratification of AKI
Prediction of clinical outcomes (dialysis, in-hospital death, length of hospital stay, mortality)
Monitor response to therapy