D-Dimer is a fibrin degradation product (or FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. D-Dimer doesn’t normally present in human blood plasma, except when the coagulation system has been activated, for instance, because of the presence of thrombosis or disseminated intravascular coagulation. It is regarded as a specific fibrinolytic process marker. D-Dimer concentration is used for suspected thrombotic disorders. While a negative result practically rules out thrombosis, a positive result can indicate thrombosis but does not rule out other potential causes. Its main use, therefore, is to exclude thromboembolic disease where the probability is low. In addition, it is used in the diagnosis of the blood disorder disseminated intravascular coagulation. Myocardial infarction, cerebral infarction, pulmonary embolism, venous thrombosis, surgery, cancer, disseminated intravascular coagulation, infection, and tissue necrosis may lead to elevated concentration of D-Dimer. Increased concentration of D-Dimer may also be observed in elderly and hospitalized patients with abnormal coagulation caused by bacteremia [1-3].

√ Equipped with special dropper consumables, the operation is easier and more suitable for clinical use

Clinical significance

√ Monitor thrombolytic therapy

Application

2. Qianhu Wu. Detection of plasma D-Dimer and its relationship with cardiovascular disease [J]. Labeled Immunoassays and Clinical Medicine, 2000, 7 (1): 32-34.