25-OH-VD Fast Test Kit

(Immunofluorescence Assay)

Intended Use

25-OH-VD Fast Test Kit (Immunofluorescence Assay) is intended for in vitro quantitative determination of 25-OH-VD inhuman serum and plasma samples. This test may help understand the metabolic changes of bone.

About 25-OH-VD

Vitamin D3 is a fat-soluble precursor for steroid-like hormone. lt is transformed into the biologically active molecule 1,25 dihydroxy vitamin D. After being synthesized in the skin of absorbed (in chylomicrons) from the gastrointestinal (Gl) tract, most vitamin D is bound to specific carrier proteins in the blood (vitamin D-binding protein [DBP] and albumin) and transported to the liver. ln the liver, vitamin D is hydroxylated by the enzyme 25-hydroxylase (CYP2R1) to become 25(OH)D. 25(OH) D is the major circulating form of vitamin D, testing of 25(OH)D help assessing the total-body vitamin D status.

Vitamin D is a major contributor for maintaining bone health, and vitamin D deficiency is also related with immunomodulation，diabetes，kinds of cancer，cardiovascular disease, autoimmune disease, congenital immune disease.

Contents

1. For Getein1100/ Getein1180

Package specifications: 25 tests/box, 10 tests/box

1) Getein 25-OH-VD test card in a sealed pouch with desiccant

2) Disposable pipet

3) Sample diluent 1

4) User manual: 1 piece/box

5) SD card: 1 piece/box

2. For Getein1600:

Package specifications: 2×24 tests/box, 2×48 tests/box

1) Sealed cartridge with 24/48 Getein 25-OH-VD test cards

2) User manual: 1 piece/box

Materials required for Getein1600:

1) Sample diluent: 1 bottle/box

2) Box with pipette tips: 96 tips/box

3) Mixing plate: 1 piece/box

Note: Do not mix or interchange different batches of kits.

Specifications

Applicable Device

Getein1100 Immunofluorescence Quantitative Analyzer

Getein1180 Immunofluorescence Quantitative Analyzer

Getein1600 Immunofluorescence Quantitative Analyzer

Clinical Application

1. As an aid to help understand the metabolic changes of bone;

2. As an aid in the diagnosis of several inherited and acquired disorders in calcium metabolism;

3. As an aid in the determination of whether a patient is vitamin D deficient, sufficient or intoxicated.